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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP45
All Species:
12.12
Human Site:
S656
Identified Species:
20.51
UniProt:
Q70EL2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL2
NP_001073950
814
91733
S656
Q
K
Y
Q
E
E
T
S
F
A
E
K
K
V
E
Chimpanzee
Pan troglodytes
XP_001139771
814
91702
S656
Q
K
Y
Q
E
E
T
S
F
A
E
K
K
V
E
Rhesus Macaque
Macaca mulatta
XP_001085248
815
91829
S657
Q
K
Y
Q
E
E
T
S
F
A
E
K
K
V
E
Dog
Lupus familis
XP_539054
796
87704
I647
A
E
K
K
A
E
S
I
Y
T
N
A
R
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K387
813
90343
S655
R
K
C
H
K
E
T
S
S
A
E
K
K
A
G
Rat
Rattus norvegicus
Q2KJ09
826
93743
A669
R
Q
C
N
G
P
K
A
N
I
K
G
E
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
V650
S
E
K
K
P
E
G
V
Y
T
N
A
R
K
Q
Chicken
Gallus gallus
O57429
357
40913
D209
Y
G
E
V
T
L
M
D
C
L
R
L
F
T
K
Frog
Xenopus laevis
Q6PAW2
901
101274
N744
K
Q
A
S
R
L
N
N
S
N
K
G
E
K
K
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
K667
P
G
Y
K
D
G
C
K
K
A
V
Y
R
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
K670
Q
C
C
T
A
N
E
K
K
V
K
Q
N
C
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
H887
C
E
T
C
T
K
A
H
K
V
E
G
K
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPT5
1083
120752
G760
N
R
I
F
D
D
R
G
T
S
E
R
P
V
F
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
H324
Y
E
C
L
D
S
F
H
K
K
E
Q
L
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.4
72.2
N.A.
77.4
38.7
N.A.
63.7
20.1
38.5
38
N.A.
N.A.
29.3
N.A.
29.9
Protein Similarity:
100
99.7
96.6
81.5
N.A.
85.3
59.6
N.A.
75.5
29.7
56.4
56.6
N.A.
N.A.
49.1
N.A.
45.3
P-Site Identity:
100
100
100
6.6
N.A.
53.3
0
N.A.
6.6
0
0
13.3
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
46.6
N.A.
66.6
40
N.A.
40
6.6
40
33.3
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
15
0
8
8
0
36
0
15
0
8
8
% A
% Cys:
8
8
29
8
0
0
8
0
8
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
22
8
0
8
0
0
0
0
0
8
8
% D
% Glu:
0
29
8
0
22
43
8
0
0
0
50
0
15
8
22
% E
% Phe:
0
0
0
8
0
0
8
0
22
0
0
0
8
0
8
% F
% Gly:
0
15
0
0
8
8
8
8
0
0
0
22
0
0
8
% G
% His:
0
0
0
8
0
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
0
% I
% Lys:
8
29
15
22
8
8
8
15
29
8
22
29
36
29
29
% K
% Leu:
0
0
0
8
0
15
0
0
0
8
0
8
8
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
8
8
8
8
8
15
0
8
0
0
% N
% Pro:
8
0
0
0
8
8
0
0
0
0
0
0
8
0
0
% P
% Gln:
29
15
0
22
0
0
0
0
0
0
0
15
0
0
15
% Q
% Arg:
15
8
0
0
8
0
8
0
0
0
8
8
22
8
8
% R
% Ser:
8
0
0
8
0
8
8
29
15
8
0
0
0
0
0
% S
% Thr:
0
0
8
8
15
0
29
0
8
15
0
0
0
8
0
% T
% Val:
0
0
0
8
0
0
0
8
0
15
8
0
0
29
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
29
0
0
0
0
0
15
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _